Succinylcholine-induced Hyperkalemia and Beyond
نویسندگان
چکیده
منابع مشابه
Succinylcholine-induced Hyperkalemia and Beyond
The mechanism of succinylcholine-induced hyperkalemia was studied in three lesions affecting canine gastrocnemius muscle. Dogs were treated for 1 month before study: 10 with normal activity, 5 with unilateral sciatic nerve section, active on 3 legs, 5 with unilateral cast immobilization of a hind limb and pelvis, active on 3 legs, and 7 inactive with T6 section of the spinal cord. Succinylcholi...
متن کاملPrecurarization with Rocuronium Prevents Succinylcholine induced Hyperkalemia
Background: To assess the effects of Rocuronium pretreatment on Succinylcholine induced rise in serum potassium. Methods: In this randomized controlled experimental study, sixty adults ASA I or II patients who presented for elective general surgical procedures were included. The patients were divided in two groups of thirty each by a simple randomization. Group "A" received succinylcholine and ...
متن کاملSuccinylcholine hyperkalemia after burns.
To the Editor-The appropriate review, "Anesthesia for Major Thermal Injury," overstates the contraindication to succinylcholine on pages 754 (". . . succinylcholine . . . >24 h after burn injury is unsafe") and 755 (". . . safe only within 24 h of a burn").' The safe period for burn patients is 6-7 days after a burn injury, whereas that for denervation is 4 days. Studies beginning 6 days after ...
متن کاملSuccinylcholine-induced hyperkalemia in patients with renal failure?
T he administration of succinylcholine (SCh) in humans results in a mild and transient hyperkalemia. In normal individuals, the increase in serum potassium (K) is approximately 0.5–1.0 mEq/L, occurs within 3–5 minutes after the IV administration of SCh, and lasts ,10–15 minutes (1). This increase is probably caused by K release from cells as a result of depolarization at the neuromuscular junct...
متن کاملSuccinylcholine-induced hyperkalemia in acquired pathologic states: etiologic factors and molecular mechanisms.
Lethal hyperkalemic response to succinylcholine continues to be reported, but the molecular mechanisms for the hyperkalemia have not been completely elucidated. In the normal innervated mature muscle, the acetylcholine receptors (AChRs) are located only in the junctional area. In certain pathologic states, including upper or lower motor denervation, chemical denervation by muscle relaxants, dru...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2009
ISSN: 0003-3022
DOI: 10.1097/aln.0b013e3181c0ad7c